Thu, 28 Mar 2024 08:43:56 -0700WeeblyMon, 11 Apr 2022 20:12:40 GMThttps://deannasmithlab.weebly.com/news/the-smith-lab-published-a-new-study-in-frontiers-in-molecular-neuroscienceIn their new study titled "LIS1 and NDEL1 Regulate Axonal Trafficking of Mitochondria in Mature Neurons", members of the Smith lab report a novel function of LIS1 and its protein partner NDEL1 in regulating mitochondrial dynamics in adult axons, raising the possibility that defects in the LIS1/NDEL1 dynein regulatory pathway could contribute to mitochondrial diseases with axonal pathologies.

Excerpt from UofSC's Biological Science Department post.
]]>Mon, 11 Apr 2022 20:12:09 GMThttps://deannasmithlab.weebly.com/news/dr-deanna-smith-awarded-another-r21-grant-from-the-nihDr. Deanna Smith, associate professor in the Department, was just awarded a two year grant from the National Institute of Neurological Disorders and Stroke (NINDS, NIH) to address that question and study the cellular roles of LIS1 in the adult mammalian nervous system, with an emphasis on projection neurons and astrocytes.

Excerpt from UofSC's Biological Sciences Department post.
]]>Mon, 11 Apr 2022 20:10:37 GMThttps://deannasmithlab.weebly.com/news/dr-deanna-smith-awarded-an-r21-grant-from-the-nihThe Smith lab now has evidence that some missense mutations may cause less severe, but much more common, neurological disorders such as autism spectrum disorders. Dr. Deanna Smith, associate professor in the Department, was just awarded a two year grant from the National Institute of Neurological Disorders and Stroke (NINDS, NIH) to study how these mutations impact LIS1’s ability to regulate dynein-dependent processes.

Excerpt from UofSC's Biological Sciences Department post.
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