Pandey JP, Shi L, Brebion RA, Smith DS. LIS1 and NDEL1 Regulate Axonal Trafficking of Mitochondria in Mature Neurons. Front. Mol. Neurosci. 2022 April 7;15:841047. doi: 10.3389/fnmol.2022.841047
Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Willis DE, Havton LA, Schiavo G, Giger RJ, Langley B, Twiss JL. Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. J Cell Biol. 2019 Jun 3;218(6):1871-1890. doi: 10.1083/jcb.201702187. Epub 2019 May 8. PubMed PMID: 31068376; PubMed Central PMCID: PMC6548128.
Piroli GG, Manuel AM, Patel T, Walla MD, Shi L, Lanci SA, Wang J, Galloway A, Ortinski PI, Smith DS, Frizzell N. Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization. Mol Cell Proteomics. 2019 Mar;18(3):504-519. doi: 10.1074/mcp.RA118.000922. Epub 2018 Dec 26. PubMed PMID: 30587509; PubMed Central PMCID: PMC6398201.
Chapman DE, Reddy BJN, Huy B, Bovyn MJ, Cruz SJS, Al-Shammari ZM, Han H, Wang W, Smith DS, Gross SP. Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528. Nat Commun. 2019 Jan 16;10(1):228. doi: 10.1038/s41467-018-08110-z. PubMed PMID: 30651536; PubMed Central PMCID: PMC6335402.
Shi L, Hines T, Bergson C, Smith D. Coupling of microtubule motors with AP-3 generated organelles in axons by NEEP21 family member calcyon. Mol Biol Cell. 2018 Aug 15;29(17):2055-2068. doi: 10.1091/mbc.E18-01-0007. Epub 2018 Jun 27. PubMed PMID: 29949458; PubMed Central PMCID: PMC6232961.
Sahoo PK, Smith DS, Perrone-Bizzozero N, Twiss JL. Axonal mRNA transport and translation at a glance. J Cell Sci. 2018 Apr 13;131(8). doi: 10.1242/jcs.196808. Review. PubMed PMID: 29654160; PubMed Central PMCID: PMC6518334.
Hines TJ, Gao X, Sahu S, Lange MM, Turner JR, Twiss JL, Smith DS. An Essential Postdevelopmental Role for Lis1 in Mice. eNeuro. 2018 Jan-Feb;5(1). doi: 10.1523/ENEURO.0350-17.2018. eCollection 2018 Jan-Feb. PubMed PMID: 29404402; PubMed Central PMCID: PMC5797476.
Shi L, Muthusamy N, Smith D, Bergson C. Dynein binds and stimulates axonal motility of the endosome adaptor and NEEP21 family member, calcyon. Int J Biochem Cell Biol. 2017 Sep;90:93-102. doi: 10.1016/j.biocel.2017.07.005. Epub 2017 Jul 19. PubMed PMID: 28734834; PubMed Central PMCID: PMC5774023.
Gao FJ, Shi L, Hines T, Hebbar S, Neufeld KL, Smith DS. Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein. Mol Biol Cell. 2017 Mar 1;28(5):587-599. doi: 10.1091/mbc.E16-07-0555. Epub 2017 Jan 5. PubMed PMID: 28057765; PubMed Central PMCID: PMC5328618.
Kalinski AL, Hines TL, Smith DS, Twiss JL. Neuronal Transport and Spatial Signaling Mechanisms in Neural Repair. In: Bradshaw RA, Stahl PD, editors. Encyclopedia of Cell Biology 3 ed. Waltham, MA: Academic Press, Elsevier, Inc.; 2016. 230-242p.
Gao FJ, Hebbar S, Gao XA, Alexander M, Pandey JP, Walla MD, Cotham WE, King SJ, Smith DS. GSK-3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility. Traffic. 2015 Sep;16(9):941-61. doi: 10.1111/tra.12304. Epub 2015 Jun 26. PubMed PMID: 26010407; PubMed Central PMCID: PMC4543430.
Pandey JP, Smith DS. A Cdk5-dependent switch regulates Lis1/Ndel1/dynein-driven organelle transport in adult axons. J Neurosci. 2011 Nov 23;31(47):17207-19. doi: 10.1523/JNEUROSCI.4108-11.2011. PubMed PMID: 22114287; PubMed Central PMCID: PMC3249231.
Hebbar S, Mesngon MT, Guillotte AM, Desai B, Ayala R, Smith DS. Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells. J Cell Biol. 2008 Sep 22;182(6):1063-71. doi: 10.1083/jcb.200803071. PubMed PMID: 18809722; PubMed Central PMCID: PMC2542469.
Hebbar S, Guillotte AM, Mesngon MT, Zhou Q, Wynshaw-Boris A, Smith DS. Genetic enhancement of the Lis1+/- phenotype by a heterozygous mutation in the adenomatous polyposis coli gene. Dev Neurosci. 2008;30(1-3):157-70. doi: 10.1159/000109860. PubMed PMID: 18075263; PubMed Central PMCID: PMC3097246.
Willis DE, van Niekerk EA, Sasaki Y, Mesngon M, Merianda TT, Williams GG, Kendall M, Smith DS, Bassell GJ, Twiss JL. Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J Cell Biol. 2007 Sep 10;178(6):965-80. doi: 10.1083/jcb.200703209. Epub 2007 Sep 4. PubMed PMID: 17785519; PubMed Central PMCID: PMC2064621.
Mesngon MT, Tarricone C, Hebbar S, Guillotte AM, Schmitt EW, Lanier L, Musacchio A, King SJ, Smith DS. Regulation of cytoplasmic dynein ATPase by Lis1. J Neurosci. 2006 Feb 15;26(7):2132-9. doi: 10.1523/JNEUROSCI.5095-05.2006. PubMed PMID: 16481446; PubMed Central PMCID: PMC4399971.
Smith D. Cdk5 in neuroskeletal dynamics. Neurosignals. 2003 Sep-Oct;12(4-5):239-51. doi: 10.1159/000074626. Review. PubMed PMID: 14673211.
Smith DS, Tsai LH. Cdk5 behind the wheel: a role in trafficking and transport?. Trends Cell Biol. 2002 Jan;12(1):28-36. doi: 10.1016/s0962-8924(01)02181-x. Review. PubMed PMID: 11854007.
Smith DS, Greer PL, Tsai LH. Cdk5 on the brain. Cell Growth Differ. 2001 Jun;12(6):277-83. Review. PubMed PMID: 11432802.
Smith DS, Leone G, DeGregori J, Ahmed MN, Qumsiyeh MB, Nevins JR. Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway. Cell Growth Differ. 2000 Dec;11(12):625-33. PubMed PMID: 11149597.
Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH. NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 2000 Dec;28(3):697-711. doi: 10.1016/s0896-6273(00)00147-1. PubMed PMID: 11163260.
Smith DS, Niethammer M, Ayala R, Zhou Y, Gambello MJ, Wynshaw-Boris A, Tsai LH. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat Cell Biol. 2000 Nov;2(11):767-75. doi: 10.1038/35041000. PubMed PMID: 11056530.
Twiss JL, Smith DS, Chang B, Shooter EM. Translational control of ribosomal protein L4 mRNA is required for rapid neurite regeneration. Neurobiol Dis. 2000 Aug;7(4):416-28. doi: 10.1006/nbdi.2000.0293. PubMed PMID: 10964612.
Hess DT, Smith DS, Patterson SI, Kahn RA, Skene JH, Norden JJ. Rapid arrest of axon elongation by brefeldin A: a role for the small GTP-binding protein ARF in neuronal growth cones. J Neurobiol. 1999 Jan;38(1):105-15. doi: 10.1002/(sici)1097-4695(199901)38:1<105::aid-neu8>3.0.co;2-m. PubMed PMID: 10027566.
Smith DS, Skene JH. A transcription-dependent switch controls competence of adult neurons for distinct modes of axon growth. J Neurosci. 1997 Jan 15;17(2):646-58. PubMed PMID: 8987787; PubMed Central PMCID: PMC6573254.
Hess DT, Patterson SI, Smith DS, Skene JH. Neuronal growth cone collapse and inhibition of protein fatty acylation by nitric oxide. Nature. 1993 Dec 9;366(6455):562-5. doi: 10.1038/366562a0. PubMed PMID: 8255294.
Landreth GE, Smith DS, McCabe C, Gittinger C. Characterization of a nerve growth factor-stimulated protein kinase in PC12 cells which phosphorylates microtubule-associated protein 2 and pp250. J Neurochem. 1990 Aug;55(2):514-23. doi: 10.1111/j.1471-4159.1990.tb04165.x. PubMed PMID: 2164572.
Smith DS, King CS, Pearson E, Gittinger CK, Landreth GE. Selective inhibition of nerve growth factor-stimulated protein kinases by K-252a and 5'-S-methyladenosine in PC12 cells. J Neurochem. 1989 Sep;53(3):800-6. doi: 10.1111/j.1471-4159.1989.tb11776.x. PubMed PMID: 2547901.
Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Willis DE, Havton LA, Schiavo G, Giger RJ, Langley B, Twiss JL. Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. J Cell Biol. 2019 Jun 3;218(6):1871-1890. doi: 10.1083/jcb.201702187. Epub 2019 May 8. PubMed PMID: 31068376; PubMed Central PMCID: PMC6548128.
Piroli GG, Manuel AM, Patel T, Walla MD, Shi L, Lanci SA, Wang J, Galloway A, Ortinski PI, Smith DS, Frizzell N. Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization. Mol Cell Proteomics. 2019 Mar;18(3):504-519. doi: 10.1074/mcp.RA118.000922. Epub 2018 Dec 26. PubMed PMID: 30587509; PubMed Central PMCID: PMC6398201.
Chapman DE, Reddy BJN, Huy B, Bovyn MJ, Cruz SJS, Al-Shammari ZM, Han H, Wang W, Smith DS, Gross SP. Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528. Nat Commun. 2019 Jan 16;10(1):228. doi: 10.1038/s41467-018-08110-z. PubMed PMID: 30651536; PubMed Central PMCID: PMC6335402.
Shi L, Hines T, Bergson C, Smith D. Coupling of microtubule motors with AP-3 generated organelles in axons by NEEP21 family member calcyon. Mol Biol Cell. 2018 Aug 15;29(17):2055-2068. doi: 10.1091/mbc.E18-01-0007. Epub 2018 Jun 27. PubMed PMID: 29949458; PubMed Central PMCID: PMC6232961.
Sahoo PK, Smith DS, Perrone-Bizzozero N, Twiss JL. Axonal mRNA transport and translation at a glance. J Cell Sci. 2018 Apr 13;131(8). doi: 10.1242/jcs.196808. Review. PubMed PMID: 29654160; PubMed Central PMCID: PMC6518334.
Hines TJ, Gao X, Sahu S, Lange MM, Turner JR, Twiss JL, Smith DS. An Essential Postdevelopmental Role for Lis1 in Mice. eNeuro. 2018 Jan-Feb;5(1). doi: 10.1523/ENEURO.0350-17.2018. eCollection 2018 Jan-Feb. PubMed PMID: 29404402; PubMed Central PMCID: PMC5797476.
Shi L, Muthusamy N, Smith D, Bergson C. Dynein binds and stimulates axonal motility of the endosome adaptor and NEEP21 family member, calcyon. Int J Biochem Cell Biol. 2017 Sep;90:93-102. doi: 10.1016/j.biocel.2017.07.005. Epub 2017 Jul 19. PubMed PMID: 28734834; PubMed Central PMCID: PMC5774023.
Gao FJ, Shi L, Hines T, Hebbar S, Neufeld KL, Smith DS. Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein. Mol Biol Cell. 2017 Mar 1;28(5):587-599. doi: 10.1091/mbc.E16-07-0555. Epub 2017 Jan 5. PubMed PMID: 28057765; PubMed Central PMCID: PMC5328618.
Kalinski AL, Hines TL, Smith DS, Twiss JL. Neuronal Transport and Spatial Signaling Mechanisms in Neural Repair. In: Bradshaw RA, Stahl PD, editors. Encyclopedia of Cell Biology 3 ed. Waltham, MA: Academic Press, Elsevier, Inc.; 2016. 230-242p.
Gao FJ, Hebbar S, Gao XA, Alexander M, Pandey JP, Walla MD, Cotham WE, King SJ, Smith DS. GSK-3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility. Traffic. 2015 Sep;16(9):941-61. doi: 10.1111/tra.12304. Epub 2015 Jun 26. PubMed PMID: 26010407; PubMed Central PMCID: PMC4543430.
Pandey JP, Smith DS. A Cdk5-dependent switch regulates Lis1/Ndel1/dynein-driven organelle transport in adult axons. J Neurosci. 2011 Nov 23;31(47):17207-19. doi: 10.1523/JNEUROSCI.4108-11.2011. PubMed PMID: 22114287; PubMed Central PMCID: PMC3249231.
Hebbar S, Mesngon MT, Guillotte AM, Desai B, Ayala R, Smith DS. Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells. J Cell Biol. 2008 Sep 22;182(6):1063-71. doi: 10.1083/jcb.200803071. PubMed PMID: 18809722; PubMed Central PMCID: PMC2542469.
Hebbar S, Guillotte AM, Mesngon MT, Zhou Q, Wynshaw-Boris A, Smith DS. Genetic enhancement of the Lis1+/- phenotype by a heterozygous mutation in the adenomatous polyposis coli gene. Dev Neurosci. 2008;30(1-3):157-70. doi: 10.1159/000109860. PubMed PMID: 18075263; PubMed Central PMCID: PMC3097246.
Willis DE, van Niekerk EA, Sasaki Y, Mesngon M, Merianda TT, Williams GG, Kendall M, Smith DS, Bassell GJ, Twiss JL. Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J Cell Biol. 2007 Sep 10;178(6):965-80. doi: 10.1083/jcb.200703209. Epub 2007 Sep 4. PubMed PMID: 17785519; PubMed Central PMCID: PMC2064621.
Mesngon MT, Tarricone C, Hebbar S, Guillotte AM, Schmitt EW, Lanier L, Musacchio A, King SJ, Smith DS. Regulation of cytoplasmic dynein ATPase by Lis1. J Neurosci. 2006 Feb 15;26(7):2132-9. doi: 10.1523/JNEUROSCI.5095-05.2006. PubMed PMID: 16481446; PubMed Central PMCID: PMC4399971.
Smith D. Cdk5 in neuroskeletal dynamics. Neurosignals. 2003 Sep-Oct;12(4-5):239-51. doi: 10.1159/000074626. Review. PubMed PMID: 14673211.
Smith DS, Tsai LH. Cdk5 behind the wheel: a role in trafficking and transport?. Trends Cell Biol. 2002 Jan;12(1):28-36. doi: 10.1016/s0962-8924(01)02181-x. Review. PubMed PMID: 11854007.
Smith DS, Greer PL, Tsai LH. Cdk5 on the brain. Cell Growth Differ. 2001 Jun;12(6):277-83. Review. PubMed PMID: 11432802.
Smith DS, Leone G, DeGregori J, Ahmed MN, Qumsiyeh MB, Nevins JR. Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway. Cell Growth Differ. 2000 Dec;11(12):625-33. PubMed PMID: 11149597.
Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH. NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 2000 Dec;28(3):697-711. doi: 10.1016/s0896-6273(00)00147-1. PubMed PMID: 11163260.
Smith DS, Niethammer M, Ayala R, Zhou Y, Gambello MJ, Wynshaw-Boris A, Tsai LH. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat Cell Biol. 2000 Nov;2(11):767-75. doi: 10.1038/35041000. PubMed PMID: 11056530.
Twiss JL, Smith DS, Chang B, Shooter EM. Translational control of ribosomal protein L4 mRNA is required for rapid neurite regeneration. Neurobiol Dis. 2000 Aug;7(4):416-28. doi: 10.1006/nbdi.2000.0293. PubMed PMID: 10964612.
Hess DT, Smith DS, Patterson SI, Kahn RA, Skene JH, Norden JJ. Rapid arrest of axon elongation by brefeldin A: a role for the small GTP-binding protein ARF in neuronal growth cones. J Neurobiol. 1999 Jan;38(1):105-15. doi: 10.1002/(sici)1097-4695(199901)38:1<105::aid-neu8>3.0.co;2-m. PubMed PMID: 10027566.
Smith DS, Skene JH. A transcription-dependent switch controls competence of adult neurons for distinct modes of axon growth. J Neurosci. 1997 Jan 15;17(2):646-58. PubMed PMID: 8987787; PubMed Central PMCID: PMC6573254.
Hess DT, Patterson SI, Smith DS, Skene JH. Neuronal growth cone collapse and inhibition of protein fatty acylation by nitric oxide. Nature. 1993 Dec 9;366(6455):562-5. doi: 10.1038/366562a0. PubMed PMID: 8255294.
Landreth GE, Smith DS, McCabe C, Gittinger C. Characterization of a nerve growth factor-stimulated protein kinase in PC12 cells which phosphorylates microtubule-associated protein 2 and pp250. J Neurochem. 1990 Aug;55(2):514-23. doi: 10.1111/j.1471-4159.1990.tb04165.x. PubMed PMID: 2164572.
Smith DS, King CS, Pearson E, Gittinger CK, Landreth GE. Selective inhibition of nerve growth factor-stimulated protein kinases by K-252a and 5'-S-methyladenosine in PC12 cells. J Neurochem. 1989 Sep;53(3):800-6. doi: 10.1111/j.1471-4159.1989.tb11776.x. PubMed PMID: 2547901.